Compile Data Set for Download or QSAR
Found 6 of Enz. Inhib. data with enzyme = 'Aurora kinase B' and Substrate = 'CHOCKtide'
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12983(5-Amido-pyrrolopyrazole 9b | CHEMBL385872 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 48nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12985(5-Amido-pyrrolopyrazole 9d | CHEMBL402548 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 79nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12984(4-(4-methylpiperazin-1-yl)-N-{5-[(2R)-2-phenylprop...)copy SMILEScopy InChI
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12982(5-Amido-pyrrolopyrazole 9a | CHEMBL385266 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12987(5-Amido-pyrrolopyrazole 9f | CHEMBL384575 | N-{5-[...)copy SMILEScopy InChI
Affinity DataIC50: 630nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed
TargetAurora kinase B(Homo sapiens (Human))
Nerviano Medical Sciences

LigandPNGBDBM12986(4-(4-methylpiperazin-1-yl)-N-{5-[(2S)-2-phenylprop...)copy SMILEScopy InChI
Affinity DataIC50: 1.21E+3nMpH: 7.5 T: 2°CAssay Description:The biochemical activity of compounds was determined by incubation with specific enzymes and substrates in the presence ATP/[gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NS0S4RPubMed